Neonatal Hypoglycaemia

Neonatal Hypoglycaemia is one of the most common metabolic challenges in the newborn period and a leading preventable cause of neurologic injury when unrecognised or untreated. This session explores mechanisms, risk factors, screening strategies, treatment thresholds, and long-term implications for infants experiencing low blood glucose in the hours and days after birth.

Clinicians routinely search for an Neonatology Conference to update their knowledge on guidelines, feeding-based prevention, buccal dextrose gel, IV glucose therapy, and monitoring protocols for at-risk newborns. This session examines infants affected by maternal diabetes, SGA status, LGA status, prematurity, perinatal stress, sepsis, endocrine disorders, and inborn errors of metabolism. Participants will learn how to interpret glucose trends, differentiate transient from persistent hypoglycaemia, and recognise signs of instability.

A key focus is creating safe, standardised pediatric neonatal hypoglycaemia pathways that integrate screening, bedside decision-making, feeding strategies, and escalation plans. Case examples illustrate how combining early breastfeeding support, frequent feeds, skin-to-skin care, and targeted supplementation significantly reduces NICU transfers. Participants will review the role of dextrose gel, when IV therapy becomes essential, and how to avoid overtreatment or unnecessary separation of mother and infant.

The session also highlights the long-term developmental effects associated with prolonged or recurrent hypoglycaemia and the importance of documenting episodes clearly for follow-up services. Attendees will explore global variations in screening guidelines, access to glucose monitoring, and strategies for supporting low-resource or rural birth centres. By the end, participants will feel confident in delivering safe, evidence-based metabolic care for newborns at risk of hypoglycaemia.

Core Themes in Neonatal Hypoglycaemia

Risk factors and physiologic adaptations

  • Understanding newborn glucose regulation and transitional physiology.
  • Identifying infants at risk based on maternal, fetal, and perinatal factors.

Screening workflows and thresholds

  • Timing glucose checks based on feeding, gestation, and clinical signs.
  • Applying evidence-based intervention thresholds while avoiding unnecessary tests.

Feeding-based intervention strategies

  • Supporting early breastfeeding, hand-expressed colostrum, and supplemental feeds.
  • Using dextrose gel appropriately to stabilise glucose without NICU separation.

Escalation and differential diagnosis

  • Recognising when glucose patterns suggest endocrine or metabolic disorders.
  • Determining when IV therapy or NICU transfer is essential.

Practice Insights and Care Pathways

Designing standardised hypoglycaemia protocols
Creating clear, stepwise algorithms for screening, feeding, and escalation.

Strengthening family-centred care
Reducing mother–infant separation and supporting breastfeeding success.

Ensuring reliable monitoring
Training staff in point-of-care testing accuracy and result interpretation.

Improving outcomes in low-resource settings
Using simplified screening tools and community-based monitoring.

 

Supporting developmental follow-up
Documenting events accurately and ensuring long-term surveillance when indicated.

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