Maternal Immunisation and Pediatric Outcomes

Maternal vaccination is one of the most effective strategies for protecting both pregnant individuals and newborns from severe infectious diseases. Maternal Immunisation and Pediatric Outcomes explores the mechanisms, evidence, and implementation strategies for ensuring that maternal vaccines translate into measurable child-health benefits. This session highlights how antibodies transferred during pregnancy and breastfeeding protect infants during their most vulnerable months, when their immune system is immature and too young for direct vaccination.

Clinicians, researchers, and public-health teams increasingly look for an Neonatology Conference to stay current with expanding evidence for pertussis, influenza, COVID-19, RSV, and emerging candidate vaccines. In this session, participants will review how vaccine timing affects antibody levels at birth, how breast milk contributes to mucosal immunity, and how maternal immunisation lowers neonatal hospitalisation and mortality. The discussion also addresses safety data, vaccine hesitancy in pregnancy, and communication strategies for building confidence.

A key theme is understanding how pediatric vaccine outcomes relate not only to biological protection but also to improved healthcare utilisation, reduced antibiotic exposure, and better early-life respiratory health. Case examples illustrate how maternal immunisation acts as the first link in the child’s immunisation journey, reinforcing vaccine acceptance and strengthening caregiver trust in pediatric care. The session will explore disparities in access to antenatal vaccination, barriers faced by migrant families, and strategies that ensure equitable reach.

Participants will further analyse how health systems can integrate maternal immunisation into routine antenatal care. This includes training obstetric providers, using electronic reminders, linking obstetric and pediatric records, and establishing mechanisms for postpartum follow-up. Attention is given to aligning messaging among obstetricians, midwives, pediatricians, nurses, and community health workers so families receive consistent, evidence-based advice. By the end of the session, attendees will gain a deep understanding of how maternal immunisation strengthens early-life health and what systems must be in place to optimise pediatric outcomes.

Core Themes in Maternal Immunisation and Pediatric Outcomes

Biological foundations of maternal immunity

  • Understanding placental antibody transfer and factors that influence neonatal antibody levels.
  • Recognising the role of breast milk immunity in shaping early protection from respiratory and gastrointestinal infections.

Impact on neonatal and infant health

  • Evaluating evidence for reduced hospitalisations, severe infections, and early-life complications.
  • Exploring long-term respiratory and immune benefits associated with maternal vaccination.

Safety and communication strategies

  • Reviewing global data confirming vaccine safety in pregnancy across multiple platforms.
  • Using empathetic, evidence-based messaging to address hesitancy and common misconceptions.

Equity and access considerations

  • Identifying populations with lower uptake due to structural, cultural, or informational barriers.
  • Designing tailored outreach programs, community partnerships, and multilingual education materials.

Practice Insights and Implementation Strategies

Integrating vaccination into antenatal workflows
Embedding vaccine screening, counselling, and administration into routine prenatal visits.

Strengthening provider confidence and alignment
Ensuring consistent messaging across obstetric, midwifery, and pediatric teams.

Tracking maternal and neonatal outcomes
Using linked health records to monitor vaccine uptake, side effects, and infant outcomes.

Addressing barriers and hesitancy
Designing supportive, non-judgmental conversations that explore concerns and build trust.

Planning postpartum follow-up
Connecting immunised mothers with pediatric vaccination schedules and early-life preventive care.

 

Supporting vulnerable and migrant populations
Using interpreters, cultural mediators, and community networks to improve vaccine accessibility.

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